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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFRC
All Species:
12.73
Human Site:
T657
Identified Species:
25.45
UniProt:
P02786
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02786
NP_001121620.1
760
84871
T657
F
R
A
T
S
R
L
T
T
D
F
G
N
A
E
Chimpanzee
Pan troglodytes
XP_001137174
750
84310
T647
T
E
I
A
S
K
F
T
E
R
L
Q
D
F
D
Rhesus Macaque
Macaca mulatta
XP_001101316
759
84759
T656
F
R
A
T
S
R
L
T
T
D
F
R
N
A
E
Dog
Lupus familis
XP_546952
806
88711
R689
I
R
A
A
E
K
L
R
K
E
I
Y
S
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q62351
763
85713
T660
F
R
A
T
S
R
L
T
T
D
F
H
N
A
E
Rat
Rattus norvegicus
Q99376
622
70134
R530
H
N
A
E
K
T
N
R
F
V
M
R
E
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516658
498
55112
K406
Q
N
A
E
S
E
N
K
F
I
T
R
L
I
N
Chicken
Gallus gallus
Q90997
776
85640
R673
Q
R
A
V
T
A
L
R
R
D
I
A
N
S
D
Frog
Xenopus laevis
NP_001089576
754
85283
H651
T
E
A
S
D
G
L
H
Q
R
L
E
H
L
D
Zebra Danio
Brachydanio rerio
NP_001009917
770
84979
T667
D
R
A
A
S
A
L
T
S
A
I
R
N
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91406
770
85483
Q661
L
T
M
S
K
K
F
Q
E
T
I
H
F
T
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M1S8
705
77149
K613
L
K
G
K
S
Y
S
K
N
D
V
A
A
A
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.5
94.4
41.8
N.A.
76.9
61.9
N.A.
41.4
52.8
24
44.4
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
100
42.3
96.9
57.9
N.A.
87.5
74
N.A.
51.4
69.7
43.2
64.9
N.A.
N.A.
N.A.
38.8
N.A.
P-Site Identity:
100
13.3
93.3
26.6
N.A.
93.3
6.6
N.A.
13.3
33.3
13.3
40
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
33.3
93.3
53.3
N.A.
93.3
6.6
N.A.
13.3
53.3
33.3
60
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
75
25
0
17
0
0
0
9
0
17
9
34
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
0
0
0
42
0
0
9
0
34
% D
% Glu:
0
17
0
17
9
9
0
0
17
9
0
9
9
0
34
% E
% Phe:
25
0
0
0
0
0
17
0
17
0
25
0
9
9
0
% F
% Gly:
0
0
9
0
0
9
0
0
0
0
0
9
0
0
0
% G
% His:
9
0
0
0
0
0
0
9
0
0
0
17
9
0
0
% H
% Ile:
9
0
9
0
0
0
0
0
0
9
34
0
0
17
0
% I
% Lys:
0
9
0
9
17
25
0
17
9
0
0
0
0
0
0
% K
% Leu:
17
0
0
0
0
0
59
0
0
0
17
0
9
9
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
17
0
9
0
0
0
42
0
17
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
17
0
0
0
0
0
0
9
9
0
0
9
0
0
9
% Q
% Arg:
0
50
0
0
0
25
0
25
9
17
0
34
0
0
0
% R
% Ser:
0
0
0
17
59
0
9
0
9
0
0
0
9
25
0
% S
% Thr:
17
9
0
25
9
9
0
42
25
9
9
0
0
9
0
% T
% Val:
0
0
0
9
0
0
0
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _